Thermo Fisher Scientific DCAF6 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 460-650 of human IQWD1 (NP_0010179771) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:DCAF6,uniProtId:Q58WW2-1,ncbiNodeId:9606,antigenRange:460-650,antigenLength:860,antigenImageFileName:PA5-89724_DCAF6_Q58WW2-1_Rabbit.svg,antigenImageFileNamePDP:PA5-89724_DCAF6_Q58WW2-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.36 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2805746

Product Specific Information

Immunogen sequence: DNNNEKLSPK PGTGEPVLSL HYSTEGTTTS TIKLNFTDEW SSIASSSRGI GSHCKSEGQE ESFVPQSSVQ PPEGDSETKA PEESSEDVTK YQEGVSAENP VENHINITQS DKFTAKPLDS NSGERNDLNL DRSCGVPEES ASSEKAKEPE TSDQTSTESA TNENNTNPEP QFQTEATGPS AHEETSTRDS A; Positive Samples: HeLa, LO2; Cellular Location: Nucleus

Target Information

NRIP is a novel 860a.a nuclear protein consisting of seven conserved WD40 domains and one NLS motif. It binds to androgen and glucocorticoid receptors and up regulates their transcriptional activity, thereby functioning as a nuclear receptor coactivator. Role of NRIP has been implicated in cell growth and also in cervical and prostrate cancer thus indicating a therapeutic intervention. Northern Blot analysis detected a high expression of NRIP in skeletal muscle and testis and low expression in heart, prostrate and adrenal gland.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.