Thermo Fisher Scientific KNT1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.01-2 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

5-20 µg/mL

-

Product Specifications

Species Reactivity

Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein T-Kininogen 1. The antigen corresponds to amino acid range 378-430 of the target protein. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:KNT1,uniProtId:P08934-1,ncbiNodeId:10114,antigenRange:378-430,antigenLength:639,antigenImageFileName:PA5-119465_KNT1_P08934-1_Rabbit.svg,antigenImageFileNamePDP:PA5-119465_KNT1_P08934-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS with 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2903963

Target Information

KNT1 (T-Kinninogen 1) is the acute phase kininogen of the rat. KNT1 could be a healing protein because of its properties as a cysteine protease inhibitor. Evidence has been presented that mRNA of T-kininogen synthesis may be a function of interleukin 6 production. In rats, four types of kininogens are produced, two of which are classical high and low molecular weight kininogens and two of which are low molecular weight-like kininogens, designated T-kininogen 1 and T-kininogen 2. T-kininogen 1 and T-kininogen 2 are 430 amino acid secreted rat proteins that each contain three cystatin domains and have nearly identical functions. Existing in plasma, both T-kininogen 1 and T-kininogen 2 are glycoproteins that act as thiol protease inhibitors and also play a role in blood coagulation, specifically by helping to optimally position blood coagulation factors.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.