Thermo Fisher Scientific TL1A Polyclonal Antibody
TL1A 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF에 사용 가능. Human 반응성, 항원 친화 크로마토그래피로 정제, 액상 형태로 -20°C 보관. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–20 µg/mL |
| Immunocytochemistry (ICC/IF) | 5–20 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein TNF Like Ligand 1A (amino acids 67–251 of target protein) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903964 |
Target Information
The protein encoded by this gene is a cytokine belonging to the tumor necrosis factor (TNF) ligand family. It is abundantly expressed in endothelial cells but not in B or T cells. Expression is inducible by TNF and IL-1 alpha. This cytokine binds to receptors TNFRSF25 and TNFRSF21/DR6, activates NF-kappaB and MAP kinases, and induces apoptosis in endothelial cells. It also inhibits endothelial cell proliferation, functioning as an angiogenesis inhibitor. An additional isoform from an alternatively spliced transcript variant has been reported, but its sequence is undetermined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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