Thermo Fisher Scientific LAMB2 Monoclonal Antibody (OTI3B4), TrueMAB
인간 LAMB2 단백질을 인식하는 마우스 단클론 항체로, Western blot 및 면역조직화학(IHC) 분석에 적합합니다. 고순도의 액상 포맷으로 제공되며, PBS/BSA/glycerol 완충액에 보존됩니다. 연구용으로만 사용 가능합니다.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific LAMB2 Monoclonal Antibody (OTI3B4), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3B4 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 314-561 of human LAMB2 produced in E.coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
Nuclear lamins form a network of intermediate-type filaments at the nucleoplasmic side of the nuclear membrane. Two main subtypes of nuclear lamins can be distinguished: A-type lamins and B-type lamins.
The A-type lamins comprise three proteins arising from the same gene by alternative splicing—lamin A, lamin C, and lamin Adel 10—while the B-type lamins include two proteins arising from distinct genes, lamin B1 and lamin B2.
Mutations in A-type lamins are associated with several rare dominant genetic disorders, including Emery-Dreifuss muscular dystrophy, dilated cardiomyopathy with conduction-system disease, and Dunnigan-type familial partial lipodystrophy.
Expression of A-type lamins correlates with cell differentiation and chromatin interaction, suggesting a role in the regulation of differential gene expression.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.