Thermo Fisher Scientific MYOZ1 Monoclonal Antibody (OTI8A1), TrueMAB
MYOZ1 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot에 최적화되어 있습니다. 사람, 생쥐, 랫트 반응성을 가지며, 동결건조 형태로 제공됩니다. 연구용으로만 사용되며, 근육 단백질 티틴 관련 연구에 적합합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8A1 |
| Immunogen | Human recombinant protein fragment (aa 106–299 of human MYOZ1) produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Sarcomere assembly is regulated by the muscle protein titin, a giant elastic protein with kinase activity that spans half the sarcomere length. MYOZ1 encodes a protein found in striated and cardiac muscle that binds to the titin Z1–Z2 domains and serves as a substrate for titin kinase. These interactions are critical for sarcomere assembly. Mutations in MYOZ1 are associated with limb-girdle muscular dystrophy type 2G.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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