Thermo Fisher Scientific MYOZ1 Monoclonal Antibody (OTI8A1), TrueMAB

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

Sarcomere assembly is regulated by the muscle protein titin, a giant elastic protein with kinase activity that spans half the sarcomere length. MYOZ1 encodes a protein found in striated and cardiac muscle that binds to the titin Z1–Z2 domains and serves as a substrate for titin kinase. These interactions are critical for sarcomere assembly. Mutations in MYOZ1 are associated with limb-girdle muscular dystrophy type 2G.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.