Thermo Fisher Scientific MYOZ1 Monoclonal Antibody (OTI3B5), TrueMAB
MYOZ1 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot에 최적화됨. Human, Mouse, Rat 반응성 보유. Lyophilized 형태로 제공되며, PBS buffer와 trehalose 포함. 근육 단백질 연구 및 사코메어 조립 관련 연구에 적합.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3B5 |
| Immunogen | Human recombinant protein fragment (amino acids 106–299 of human MYOZ1) produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- For reconstitution, add 100 µL distilled water to achieve a final concentration of ~1 mg/mL.
- For conjugation experiments, perform additional desalting (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Sarcomere assembly is regulated by the muscle protein titin, a giant elastic protein with kinase activity that spans half the sarcomere length. Titin acts as a scaffold for myofibrils and muscle-related proteins.
MYOZ1 encodes a protein found in striated and cardiac muscle that binds to titin Z1–Z2 domains and serves as a substrate for titin kinase. These interactions are critical for sarcomere assembly.
Mutations in MYOZ1 are associated with limb-girdle muscular dystrophy type 2G.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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