Thermo Fisher Scientific ARHGAP18 Polyclonal Antibody
ARHGAP18 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunocytochemistry에 적합합니다. Human, Mouse, Rat 시료 반응성이 있으며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로 세포 신호전달 및 단백질 발현 연구에 활용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 2.5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 15 amino acid peptide near the carboxy terminus of human ARHGAP18 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11157644 |
Product Specific Information
- Suggested positive control: NIH-3T3 cell lysate
- PA5-20893 can be used with blocking peptide PEP-1007
Target Information
ARHGAP18 is a member of the human RhoGAP family, which includes approximately 80 RhoGAP proteins encoded in the human genome.
Rho proteins belong to the Ras superfamily, composed of over 50 members divided into six families: Ras, Sar, Rho, Ran, Rab, and Arf.
Rho GTPases regulate the actin cytoskeleton and influence cell shape and migration.
ARHGAP18 is linked to Ras and EGFR-mediated proliferation, migration, and differentiation.
It is located on chromosome 6q22–24, a region associated with schizophrenia, suggesting a potential role for ARHGAP18 in this condition.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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