Thermo Fisher Scientific RASD2 Polyclonal Antibody
RASD2 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC, ELISA 등 다양한 응용에 사용 가능. Human, Mouse, Rat 반응성. Protein A 정제, 1 mg/mL 농도, -20°C 보관. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:400 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human RASD2/Tumor endothelial marker 2 (amino acids 201–266) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Rhes, also known as tumor endothelial marker 2 (TEM2), is a small GTP-binding protein predominantly expressed in the striatal region of the brain. It belongs to the RASD subfamily of Ras-related GTP-binding proteins and is implicated in normal brain development and function. Mice lacking this gene show increased anxiety and motor coordination deficits. Rhes was identified as TEM2 through analysis of genes upregulated in tumor endothelium. Tumor endothelial markers are significantly upregulated during angiogenesis and neoangiogenesis, processes crucial for solid tumor growth. TEMs localized on the cell surface and conserved across species are of interest for developing anti-angiogenic therapies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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