Thermo Fisher Scientific CD66 Recombinant Mouse Monoclonal Antibody (A5B7)
Thermo Fisher Scientific의 CD66 (CEACAM) 재조합 마우스 단클론 항체(A5B7)는 인간 CEA에 특이적입니다. WB, IHC, ICC, Flow Cytometry 등 다양한 응용에 사용 가능하며, Protein A로 정제된 1 mg/mL 액상 형태입니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.01 µg/mL |
| Immunohistochemistry (IHC) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| Flow Cytometry (Flow) | 1:100 |
| Functional Assay | Assay-dependent |
| Radioimmune Assay (RIA) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | A5B7 |
| Immunogen | Raised by immunising mice with carcinoembryonic antigen (CEA) purified from metastases of colonic tumours and heat-treated CEA. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3074623 |
Product Specific Information
Specificity: This antibody is specific for human carcinoembryonic antigen (CEA).
Target Information
CD66 molecules are 180–200 kDa glycoproteins of the carcinoembryonic antigen family. They are present on all blood granulocytes and some tissue macrophages but absent from other hematopoietic cells. Expression of CD66 increases significantly upon granulocyte activation.
- CD66a (BGP1, CEACAM1), CD66d (CGM1, CEACAM3), CEACAM2, and CEACAM4 are transmembrane proteins.
- CD66c (CEAL, NCA, CEACAM6), CD66e (CEA, CEACAM5), CEACAM7, and CEACAM8 are anchored to the plasma membrane by a C-terminal GPI lipid moiety.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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