Thermo Fisher Scientific CD66 Recombinant Mouse Monoclonal Antibody (A5B7)

Applications

Tested Dilution

Publications

Western Blot (WB)

0.01 µg/mL

-

Immunohistochemistry (IHC)

Assay-dependent

-

Immunocytochemistry (ICC/IF)

10 µg/mL

-

Flow Cytometry (Flow)

1:100

-

Functional Assay (Functional)

Assay-dependent

-

Radioimmune Assays (RIA)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1, kappa

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

A5B7

Immunogen

This antibody was raised by immunising mice with both carcinoembryonic antigen (CEA) purified from the metastases of colonic tumours, and heat-treated CEA. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CD66 (CEACAM),uniProtId:P06731-1,ncbiNodeId:9606,antigenRange:1-702,antigenLength:702,antigenImageFileName:MA5-48180_CD66_CEACAM_P06731-1_House_mouse.svg,antigenImageFileNamePDP:MA5-48180_CD66_CEACAM_P06731-1_House_mouse_PDP.jpeg,sortOrder:1},{targetFamily:CD66 (CEACAM),uniProtId:O75871-1,ncbiNodeId:9606,antigenRange:1-244,antigenLength:244,antigenImageFileName:MA5-48180_CD66_CEACAM_O75871-1_House_mouse.svg,antigenImageFileNamePDP:MA5-48180_CD66_CEACAM_O75871-1_House_mouse_PDP.jpeg,sortOrder:2},{targetFamily:CD66 (CEACAM),uniProtId:P13688-1,ncbiNodeId:9606,antigenRange:1-526,antigenLength:526,antigenImageFileName:MA5-48180_CD66_CEACAM_P13688-1_House_mouse.svg,antigenImageFileNamePDP:MA5-48180_CD66_CEACAM_P13688-1_House_mouse_PDP.jpeg,sortOrder:3},{targetFamily:CD66 (CEACAM),uniProtId:P40198-1,ncbiNodeId:9606,antigenRange:1-252,antigenLength:252,antigenImageFileName:MA5-48180_CD66_CEACAM_P40198-1_House_mouse.svg,antigenImageFileNamePDP:MA5-48180_CD66_CEACAM_P40198-1_House_mouse_PDP.jpeg,sortOrder:4},{targetFamily:CD66 (CEACAM),uniProtId:P40199-1,ncbiNodeId:9606,antigenRange:1-344,antigenLength:344,antigenImageFileName:MA5-48180_CD66_CEACAM_P40199-1_House_mouse.svg,antigenImageFileNamePDP:MA5-48180_CD66_CEACAM_P40199-1_House_mouse_PDP.jpeg,sortOrder:5}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS

Contains

0.02% ProClin 300

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_3074623

Product Specific Information

Specificity: This antibody is specific for human CEA.

Target Information

The CD66 molecules are 180-200 kDa glycoproteins of carcinoembryonic antigen family. They are present on all blood granulocytes and some tissue macrophages, but are absent from other hematopoietic cells. The expression of CD66 increases significantly on granulocytes upon their activation. CD66a (BGP1, CEACAM1) and CD66d (CGM1, CEACAM3), as well as CEACAM2 and 4, are transmembrane proteins, whereas CD66c (CEAL, NCA, CEACAM6) and CD66e (CEA, CEACAM5), as well as CEACAM7 and 8, are anchored to the plasma membrane by C-terminal glycosylphosphatidylinositol (GPI) lipid moiety.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.