Thermo Fisher Scientific CD4 Recombinant Mouse Monoclonal Antibody (DB81)
인간 CD4 단백질을 인식하는 재조합 마우스 단클론 항체로, Flow Cytometry, ELISA, Neutralization 등 다양한 분석에 사용 가능. HEK293 세포에서 발현되며 Protein A로 정제됨. 인간 및 침팬지 CD4에 반응하며 HIV 연구에 적합.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CD4 Recombinant Mouse Monoclonal Antibody (DB81)
Applications
Flow Cytometry (Flow)
- Tested Dilution: Assay-dependent
ELISA (ELISA)
- Tested Dilution: Assay-dependent
Neutralization (Neu)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | DB81 |
| Immunogen | This antibody was raised by immunising BALB/c mice with human CD4 complexed with HIV-1 Env (gp120). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3074625 |
Product Specific Information
Specificity: This antibody is specific for human CD4 and recognises an epitope in the vicinity of a 13-amino acid loop in domain 2 of CD4. It cross-reacts with chimpanzee CD4, but not baboon or macaque CD4.
Target Information
The CD4 antigen is involved in the recognition of MHC class II molecules and acts as a co-receptor for HIV. CD4 is primarily expressed in T helper cells, but also in monocytes, macrophages, and dendritic cells. At the tissue level, CD4 expression is found in thymus, lymph nodes, tonsils, spleen, and specific regions of brain and gut. CD4 functions to initiate or augment early T-cell activation through association with the T-cell receptor complex and tyrosine kinase Lck. It may also mediate neuronal damage in infectious and immune-mediated CNS diseases. Multiple alternatively spliced transcripts have been identified (RefSeq, July 2017).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.