
Thermo Fisher Scientific Phospho-eIF2b epsilon (Ser540) Polyclonal Antibody
eIF2B epsilon의 Ser540 인산화 형태를 특이적으로 인식하는 Rabbit Polyclonal Antibody. Western blot 및 IHC(Paraffin)에서 검증됨. PBS/glycerol buffer에 보관하며, -20°C에서 안정적. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human EIF2B5 (Accession Q13144), corresponding to amino acid residues around phosphorylated Ser540. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2817331 |
Product Specific Information
This antibody detects endogenous levels of eIF2B epsilon only when phosphorylated at Ser540.
Target Information
This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (eIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator of protein synthesis. Mutations in this gene and those encoding other EIF2B subunits are associated with leukoencephalopathy with vanishing white matter.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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