Thermo Fisher Scientific Phospho-RARA/RARB (Ser96) Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:3,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human RARA(Accession P10276), corresponding to amino acid residues around phosphorylated Ser96. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:RARA/RARB,uniProtId:P10276-1,ncbiNodeId:9606,antigenRange:96,antigenLength:462,antigenImageFileName:PA5-105934_RARARARB_P10276-1_Rabbit.svg,antigenImageFileNamePDP:PA5-105934_RARARARB_P10276-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2817333

Product Specific Information

Antibody detects endogenous levels of Retinoic Acid Receptor alpha/beta only when phosphorylated at Retinoic AcSer96.

Target Information

Retinoic acid, a metabolite of vitamin A, is necessary for normal organogenesis but acts as a teratogen at high levels during embryonic and fetal development. Retinoic acid functions through its interaction with the nuclear protein, retinoic acid receptor (RAR). RAR belongs to the steroid and thyroid hormone superfamily of nuclear receptor proteins which exert their effects by binding to specific DNA response elements, thus regulating gene expression in target cells. RAR exists as three major subtypes: alpha, beta and gamma.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.