Thermo Fisher Scientific MST4 Polyclonal Antibody
MST4 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot, IHC, ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 1 mg/mL 농도의 액상 형태로 제공. 인간에 반응하며 마우스, 랫, 돼지에도 예측 반응.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region within amino acids 352–416 of MST4 (Uniprot ID: Q9P289) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11154477 |
Product Specific Information
- Recommended positive controls: A549, IMR32
- Predicted reactivity: Mouse (100%), Rat (100%), Pig (100%)
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
MST4 is a member of the Ste20-like kinase family of serine/threonine kinases and is overexpressed during prostate cancer development. The gene product belongs to the GCK group III family of kinases, containing an amino-terminal kinase domain and a carboxy-terminal regulatory domain that mediates homodimerization. MST4 localizes to the Golgi apparatus and is activated by binding to the Golgi matrix protein GM130. It is also cleaved by caspase-3 in vitro and may function in the apoptotic pathway. Several alternatively spliced transcript variants have been described.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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