
Thermo Fisher Scientific HPS3 Polyclonal Antibody
HPS3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF에 사용 가능. 높은 특이성과 재현성을 제공하며, 인체 반응성 확인. 연구용으로 Hermansky-Pudlak syndrome 관련 연구에 적합.
- 카탈로그번호
- PA521868
- 판매단위
- pk
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Thermo Fisher Scientific HPS3 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region within amino acids 942–1004 of HPS3 (Uniprot ID: Q969F9) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.92 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11154800 |
Product Specific Information
- Recommended positive controls: 293T, A431, H1299, HeLaS3, HepG2, Molt-4, Raji
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a protein containing a potential clathrin-binding motif, consensus dileucine signals, and tyrosine-based sorting signals for targeting to vesicles of lysosomal lineage.
The encoded protein may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes.
Mutations in this gene are associated with Hermansky-Pudlak syndrome type 3.
Alternate splice variants exist, but their full-length sequence has not been determined.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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