Thermo Fisher Scientific MRP2 Recombinant Rabbit Monoclonal Antibody (6L3Z6)

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:1,000

ELISA

• Tested Dilution: 1 µg/mL

Product Specifications

Product Specific Information

• Positive test controls include: HepG2, A-549.
• Immunogen sequence:
  CLGRALLRKS KILVLDEATA AVDLETDNLI QTTIQNEFAH CTVITIAHRL HTIMDSDKVM VLDNGKIIEC GSPEELLQIP GPFYFMAKEA GIENVNSTKF

Target Information

This gene encodes the prototype of the membrane-associated guanylate kinase (MAGUK) family proteins. MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intercellular junctions. The encoded protein is an extensively palmitoylated membrane phosphoprotein containing a PDZ domain, a Src homology 3 (SH3) motif, and a guanylate kinase domain. This gene product interacts with various cytoskeletal proteins and cell junctional proteins in different tissue and cell types, and may be involved in the regulation of cell shape, hair cell development, neural patterning of the retina, and apico-basal polarity and tumor suppression pathways in non-erythroid cells. Multiple transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.