Thermo Fisher Scientific MRP2 Recombinant Rabbit Monoclonal Antibody (6L3Z6)
MRP2 단백질을 인식하는 토끼 단클론 항체로 Western blot과 ELISA에 적합합니다. HEK293 세포에서 발현된 재조합 항체이며, 고순도의 Affinity Chromatography 정제 제품입니다. PBS 완충액에 보관되며 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 6L3Z6 |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 1446–1545 of human MRP2/ABCC2 (Q92887) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2912062 |
Product Specific Information
- Positive test controls include: HepG2, A-549.
- Immunogen sequence:
CLGRALLRKS KILVLDEATA AVDLETDNLI QTTIQNEFAH CTVITIAHRL HTIMDSDKVM VLDNGKIIEC GSPEELLQIP GPFYFMAKEA GIENVNSTKF
Target Information
This gene encodes the prototype of the membrane-associated guanylate kinase (MAGUK) family proteins. MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intercellular junctions. The encoded protein is an extensively palmitoylated membrane phosphoprotein containing a PDZ domain, a Src homology 3 (SH3) motif, and a guanylate kinase domain. This gene product interacts with various cytoskeletal proteins and cell junctional proteins in different tissue and cell types, and may be involved in the regulation of cell shape, hair cell development, neural patterning of the retina, and apico-basal polarity and tumor suppression pathways in non-erythroid cells. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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