Thermo Fisher Scientific PSMA Recombinant Rabbit Monoclonal Antibody (4X3O6)
PSMA 단백질을 표적으로 하는 Thermo Fisher Scientific의 재조합 토끼 단클론 항체입니다. Western blot과 Immunocytochemistry에 최적화되어 있으며, 높은 특이성과 재현성을 제공합니다. HEK293 세포 발현, 액상 형태로 -20°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500 – 1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:50 – 1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 4X3O6 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–106 of human PSMA/FOLH1 (Q04609) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.9 mg/mL |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2912065 |
Product Specific Information
- Positive test controls include: LNCaP.
Target Information
This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family.
The protein acts as a glutamate carboxypeptidase on different substrates, including folate and the neuropeptide N-acetyl-L-aspartyl-L-glutamate.
It is expressed in tissues such as the prostate, central and peripheral nervous system, and kidney.
Mutations may cause impaired folate absorption and hyperhomocysteinemia.
In the brain, expression may be linked to glutamate excitotoxicity-related conditions.
In the prostate, the protein is up-regulated in cancerous cells and serves as a diagnostic and prognostic marker for prostate cancer.
This gene likely originated from a chromosomal duplication event, and alternative splicing produces multiple isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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