Thermo Fisher Scientific PHGDH Monoclonal Antibody (OTI9C2), TrueMAB
PHGDH 단백질을 인식하는 Mouse Monoclonal 항체로 Western Blot 및 IHC(P)에서 검증됨. 인간 시료에 반응하며, TrueMAB 형식의 고품질 항체. 액상 형태로 제공되며, -20°C에서 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI9C2 |
| Immunogen | Full length human recombinant protein of human PHGDH produced in HEK293T cell. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The PHGDH gene encodes an enzyme involved in the early steps of L-serine synthesis in animal cells. L-serine is essential for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been identified in families with congenital microcephaly, psychomotor retardation, and other symptoms. Multiple alternatively spliced transcript variants have been reported, though the full-length forms of most are not known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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