Thermo Fisher Scientific ADM Monoclonal Antibody (OTI8A1), TrueMAB
인간 ADM 단백질(aa 22-146)에 특이적인 Mouse IgG2b 단클론 항체입니다. IHC(P)에서 1:250 희석으로 검증되었으며, 액상 형태로 1 mg/mL 농도로 제공됩니다. PBS/BSA/glycerol 완충액에 보관하며, -20°C에서 동결-해동을 피해야 합니다. 연구용으로만 사용 가능합니다.
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Applications
Tested Applications and Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 1:250
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8A1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 22–146 of human ADM produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Adrenomedullin (ADM) is a vasodilator produced by most contractile cells, characterized by persistent hypotensive activity. ADM is involved in the regulation of fluid and electrolyte homeostasis and maintenance of cardiovascular function. In hypertensive patients, plasma ADM levels are upregulated. ADM also exerts strong natriuretic actions by increasing glomerular filtration rate and decreasing distal tubular sodium reabsorption. It is present both in the periphery and brain, where it can reduce food intake through central effects.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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