Thermo Fisher Scientific 5HT2A Receptor Polyclonal Antibody
5HT2A 수용체를 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, WB, IHC, ELISA, IP 등 다양한 응용에 적합. Human, Mouse, Rat 반응성. 고순도 Affinity chromatography 정제, 안정적인 액상 형태로 -20°C 보관.
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Thermo Fisher Scientific 5HT2A Receptor Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 400–450 of human 5-hydroxytryptamine receptor 2A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Serotonin plays a major role in cardiovascular function and gastrointestinal motility. It exerts its effects through G protein-coupled receptors known as 5-HT or SR receptors. The SR-2 receptor family includes SR-2A, SR-2B, and SR-2C subtypes, which activate phospholipase C and release intracellular calcium in response to serotonin.
- SR-2A: Involved in tracheal smooth muscle contraction, bronchoconstriction, and aldosterone production; associated with psychiatric disorders such as depression and schizophrenia.
- SR-2B: Expressed in cardiovascular tissues, gut, and brain; plays a role in cardiac pathology.
- SR-2C: Mediates effects of atypical antipsychotic drugs.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: 5HT2A-101AP_HTR2A_P28223-1_Rabbit.svg, 5HT2A-101AP_HTR2A_P28223-1_Rabbit_PDP.jpeg)
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