Thermo Fisher Scientific TRF2 Polyclonal Antibody
TRF2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, Flow cytometry 등에 사용 가능. Human, Mouse, Rat 시료에 반응하며, 항원 친화 크로마토그래피로 정제됨. PBS/glycerol buffer에 보관하며 연구용으로 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein within Human TRF2 (aa 124–301) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2901108 |
Product Specific Information
Positive Controls: A549, LOVO, Siha, rat uterus tissue, human tonsil tissue, mouse testis tissue.
Target Information
TRF2 (Telomeric Repeat-binding Factor 2) is a ubiquitously expressed protein involved in the regulation of telomere length. It contains a Myb-related DNA binding motif and binds to duplex TTAGGG repeats, localizing to telomeres in metaphase chromosomes. TRF2 is believed to protect chromosome ends by maintaining telomere structure and preventing senescence in primary human cells. Inhibition of TRF2 has been shown to induce apoptosis in certain mammalian cell types.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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