Thermo Fisher Scientific BMP3 Polyclonal Antibody
BMP3 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot, IHC, ELISA에 적합. 인간, 마우스, 랫트 반응성. 고순도 Affinity 정제 및 안정한 PBS/glycerol buffer 보존. 골형성 관련 연구용으로 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 243–472 of human BMP3 (NP_001192.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.34 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2854861 |
Product Specific Information
Immunogen sequence:
YANDAAISEP ESVVSSLQGH RNFPTGTVPK WDSHIRAALS IERRKKRSTG VLLPLQNNEL PGAEYQYKKD EVWEERKPYK TLQAQAPEKS KNKKKQRKGP HRKSQTLQFD EQTLKKARRK QWIEPRNCAR RYLKVDFADI GWSEWIISPK SFDAYYCSGA CQFPMPKSLK PSNHATIQSI VRAVGVVPGI PEPCCVPEKM SSLSILFFDE NKNVVLKVYP NMTVESCACR
Target Information
BMPs belong to the TGF-Beta superfamily and stimulate the production of bone matrix proteins, influencing stromal cell and osteoclast proliferation—key steps in bone marrow development.
In addition to promoting ectopic bone and cartilage formation, BMPs regulate growth, differentiation, chemotaxis, proliferation, and apoptosis of various cell types, including mesenchymal, epithelial, hematopoietic, and neuronal cells.
BMPs also play a role in dorsal/ventral patterning. BMP3, highly expressed in lung, ovary, and small intestine, participates in cartilage and bone formation. BMP3 and BMP2 genes map to conserved regions between human and mouse.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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