Thermo Fisher Scientific Oct-4BOCT4B-190NT Polyclonal Antibody
Oct-4BOCT4B-190NT 폴리클로날 항체로 인간, 생쥐, 개, 쥐 시료에 반응. Western blot, IHC, ICC, Flow, ELISA 등 다양한 응용 가능. OCT4B-190 유래 합성 펩타이드로 면역화된 Rabbit IgG 항체. 단백질 A 정제, 액상 형태로 -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:100 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human OCT4B-190, amino acids 201–300 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
POU5F1, commonly known as Oct-4, is a maternally expressed octamer-binding protein and the first transcription factor described for early development. Its role in embryonic development suggests utility in creating stem cells for cell replacement therapies in degenerative diseases. Induced pluripotent stem (iPS) cells can be generated by expressing POU5F1 with Sox2, Klf4, Lin28, and c-Myc in mouse fibroblasts. Recent experiments show iPS cells can be produced using plasmids expressing these factors, eliminating viral introduction and improving safety for regenerative medicine applications.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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