Thermo Fisher Scientific WDR77 Monoclonal Antibody (OTI5E9), TrueMAB
WDR77 단백질을 인식하는 Mouse IgG1 단일클론 항체로 Western blot에 최적화됨. Human, Mouse, Rat 반응성. Lyophilized 형태로 제공되며, PBS 및 trehalose buffer 포함. 연구용으로 PRMT5 복합체 관련 단백질 분석에 적합.
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Applications
- Western Blot (WB): Tested dilution 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5E9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–250 of human WDR77 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
WDR77 is a component of the 20S PRMT5-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins. This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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