Thermo Fisher Scientific PDCL3 Monoclonal Antibody (OTI6G6), TrueMAB
PDCL3 단백질을 인식하는 마우스 단클론 항체로, Western blot에 최적화되어 있습니다. 인간, 마우스, 랫트 시료에 반응하며, 동결건조 형태로 제공됩니다. PBS 버퍼에 트레할로스가 포함되어 안정성이 높고, 연구용으로 적합합니다.
- 카탈로그번호
- CF809714
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat, Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6G6 |
| Immunogen | Full length human recombinant protein of human PDCL3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Phosducin-like proteins (PhLPs) are a conserved family of proteins with thioredoxin-like domains, initially identified as modulators of G protein signaling.
PDCL3 is highly homologous to PDCL and shares an N-terminal helix domain and a C-terminal thioredoxin-fold (Trx-fold) domain.
Together with PDCL2, PDCL3 interacts with the chaperonin CCT and modulates CCT-mediated actin and tubulin folding.
MAPK phosphorylation and RhoA-dependent regulation of PDCL3 contribute to cytoskeletal remodeling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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