Thermo Fisher Scientific FABP5 Monoclonal Antibody (FABP5, 3750)
FABP5 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, 인간 시료에 반응합니다. Western blot, IHC, Peptide array 등 다양한 응용에 적합합니다. 고순도 Protein A/G 정제, 액상 형태로 제공되며 연구용으로 사용됩니다.
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- 2171-MSM2-P1
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 0.1–0.2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | FABP5, 3750 |
| Immunogen | Recombinant full-length human FABP5 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Immunohistochemistry (PFA fixed): Incubate antibody for 30 min at room temperature.
Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA (pH 9.0) for 45 min at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
FABP5 (fatty acid binding protein 5, psoriasis-associated) is a protein encoded by the FABP5 gene in humans, also known as PAFABP, EFABP, E-FABP, KFABP, PA-FABP, Epidermal-type fatty acid-binding protein, Fatty acid-binding protein 5, and Psoriasis-associated fatty acid-binding protein homolog.
It belongs to a family of small, highly conserved cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. The PAFABP cDNA encodes a 135-amino acid protein with a molecular weight of 15,164 Da.
FABP5 is expressed in epidermal cells and was first identified as being upregulated in psoriatic tissue. Its roles include fatty acid uptake, transport, and metabolism.
Kaczocha et al. (2009) identified FABP5 and FABP7 as cytosolic proteins that transport AEA from the plasma membrane to subcellular fatty acid amide hydrolase, where it is hydrolyzed and inactivated. FABP3 did not show this specific transport function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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