Thermo Fisher Scientific JunD Polyclonal Antibody
JunD 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ELISA 등 다양한 응용에 사용 가능. Human, Mouse, Rat 반응성. 고순도 Affinity Chromatography 정제, 안정적 액상 형태로 -20°C 보관.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–190 of human JunD (NP_005345.3) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.81 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2913712 |
Product Specific Information
Positive test controls include: HeLa, Jurkat, 293T, HepG2, Mouse kidney, Mouse liver, Mouse pancreas, Mouse testis, Rat liver.
The target is usually found in the nucleus.
Immunogen sequence:
METPFYGDEA LSGLGGGASG SGGSFASPGR LFPGAPPTAA AGSMMKKDAL TLSLSEQVAA ALKPAAAPPP TPLRADGAPS AAPPDGLLAS PDLGLLKLAS PELERLIIQS NGLVTTTPTS SQFLYPKVAA SEEQEFAEGF VKALEDLHKQ NQLGAGAAAA AAAAAAGGPS GTATGSAPPG ELAPAAAAPE
Target Information
JunD is a transcription factor coded by the JunD gene. Its transcriptional activity is modulated by phosphorylation in response to cellular stress via the JNK/SAPK family of protein kinases.
Jun proteins form dimers with Fos, ATF, and CREB family transcription factors to create the AP-1 complex, which regulates genes involved in growth, proliferation, differentiation, and apoptosis.
JunD also plays an important role in metabolism through modulation of the IGF-1 signaling pathway.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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