Thermo Fisher Scientific ATF1 Polyclonal Antibody, DyLight 488
DyLight 488 형광 표지된 ATF1 폴리클로날 항체로 인간 ATF1 단백질을 특이적으로 인식합니다. Flow Cytometry에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 4°C 암소 보관, 연구용 전용 제품입니다.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 1–3 µg/1x10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E.coli-derived human ATF1 recombinant protein (Position: M1–V271) |
| Conjugate | DyLight™ 488 |
| Excitation / Emission Max | 492 / 519 nm |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE! |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745945 |
Target Information
This gene encodes an activating transcription factor belonging to the ATF subfamily and bZIP (basic-region leucine zipper) family. It regulates downstream target genes involved in cellular growth, survival, and other physiological processes. Phosphorylation at serine 63 by various kinases enhances transactivation and transcriptional activity, contributing to cell transformation. Gene fusions with FUS (chromosome 16) or EWSR1 (chromosome 22) produce chimeric proteins associated with angiomatoid fibrous histiocytoma and clear cell sarcoma. A pseudogene exists on chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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