Thermo Fisher Scientific USP13 Monoclonal Antibody (OTI5B9), TrueMAB
USP13 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot 및 Immunoprecipitation에 적합. 동결건조 형태로 제공되며, PBS 버퍼와 trehalose 포함. 인간 단백질에 반응하며, 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunoprecipitation (IP)
- Tested Dilution: 4 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5B9 |
| Immunogen | Full-length human USP13 protein expressed in 293T cells transfected with USP13 expression vector |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
USP13 is a deubiquitinase involved in deubiquitination of target proteins such as BECN1, MITF, SKP2, and USP10.
It plays key roles in autophagy and ER-associated degradation (ERAD).
USP13 regulates p53/TP53 stability through interaction with USP10 and PIK3C3/VPS34-containing complexes.
It also mediates stabilization of SIAH2 independently of deubiquitinase activity and preferentially cleaves Lys-63-linked polyubiquitin chains.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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