Thermo Fisher Scientific Pannexin 1 Recombinant Rabbit Monoclonal Antibody (ARC1207)
Pannexin 1 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot, IHC, ELISA에 적합합니다. 인간, 생쥐, 랫트 반응성이 있으며 HEK293 세포에서 발현되었습니다. 고순도 친화 크로마토그래피 정제 및 안정적인 PBS/glycerol buffer로 보관됩니다.
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Thermo Fisher Scientific Pannexin 1 Recombinant Rabbit Monoclonal Antibody (ARC1207)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC1207 |
| Immunogen | Synthetic peptide corresponding to amino acids 327–426 of human Pannexin 1 (Q96RD7) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.21 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849564 |
Product Specific Information
Immunogen sequence:
DLSLYNLFLE ENISEVKSYK CLKVLENIKS SGQGIDPMLL LTNLGMIKMD VVDGKTPMSA EMREEQGNQT AELQGMNIDS ETKANNGEKN ARQRLLDSSC
Target Information
The pannexin gene family encodes a second class of putative gap junction proteins and is highly conserved across invertebrates and mammals. Pannexins (Panx) are four-pass transmembrane proteins that oligomerize to form large pore ion and metabolite-permeable channels.
Pannexin-1 (PANX1) and Pannexin-3 are closely related, while Pannexin-2 is more distantly related. PANX1 forms a mechanosensitive ATP-permeable channel between adjacent cells and within the endoplasmic reticulum. It may act as a Ca²⁺ leak channel to regulate ER Ca²⁺ homeostasis and neural stem/progenitor cell proliferation.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
제품 이미지
(이미지 파일명: MA5-35664_Pannexin_1_Q96RD7-1_Rabbit.svg)
(이미지 파일명: MA5-35664_Pannexin_1_Q96RD7-1_Rabbit_PDP.jpeg)
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