
Thermo Fisher Scientific DDX1 Polyclonal Antibody
DDX1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC, ELISA, IP 등 다양한 응용에 적합. Human, Mouse, Rat 반응성. 고순도 Affinity Chromatography 정제, -20°C 보관. 연구용 전용.
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Thermo Fisher Scientific DDX1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
| Immunoprecipitation (IP) | 0.5–4 µg antibody for 200–400 µg extracts |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 441–740 of human DDX1 (NP_0049301) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.33 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806612 |
Product Specific Information
Immunogen sequence:
VHHVVVPVNP KTDRLWERLG KSHIRTDDVH AKDNTRPGAN SPEMWSEAIK ILKGEYAVRA IKEHKMDQAI IFCRTKIDCD NLEQYFIQQG GGPDKKGHQF SCVCLHGDRK PHERKQNLER FKKGDVRFLI CTDVAARGID IHGVPYVINV TLPDEKQNYV HRIGRVGRAE RMGLAISLVA TEKEKVWYHV CSSRGKGCYN TRLKEDGGCT IWYNEMQLLS EIEEHLNCTI SQVEPDIKVP VDEFDGKVTY GQKRAAGGGS YKGHVDILAP TVQELAALEK EAQTSFLHLG YLPNQLFRTF
Positive Samples: MCF7, HepG2, HeLa, 293T, U-251MG, Mouse brain, Mouse skeletal muscle, Rat brain, Rat skeletal muscle
Cellular Location: Cytoplasm, Cytoplasmic granule, Nucleus
Target Information
DDX1 (ATP-dependent RNA helicase DDX1)는 RNA-RNA 및 RNA-DNA 이중가닥을 풀 수 있는 ATP 의존적 RNA helicase입니다.
5' single-stranded RNA overhang nuclease 및 RNA ATPase 활성을 가지며, RELA와 함께 NF-κB 매개 전사 활성화를 촉진하는 공동활성자로 작용합니다.
Cyclin CCND2 발현의 양성 전사 조절자로 작용하며, CCND2 프로모터 영역에 결합합니다.
DDX1은 다중 helicase-TICAM1 복합체의 구성 요소로서, 바이러스성 이중가닥 RNA의 세포질 감지 및 항바이러스 반응 유도에 관여합니다.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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