Thermo Fisher Scientific Cystatin 2 Polyclonal Antibody
Thermo Fisher Scientific의 Cystatin 2 Polyclonal Antibody는 인간 및 마우스 시료에 반응하는 Rabbit IgG 항체로, Western blot과 ELISA에 적합합니다. 고순도 친화 크로마토그래피 정제 방식으로 제조되었으며, 안정한 PBS/glycerol 버퍼에 보존됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 20–141 of human CST2 (NP_0013131) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.51 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806611 |
Product Specific Information
- Immunogen sequence:
AWSPQEEDRI IEGGIYDADL NDERVQRALH FVISEYNKAT EDEYYRRLLR VLRAREQIVG GVNYFFDIEV GRTICTKSQP NLDTCAFHEQ PELQKKQLCS FQIYEVPWED RMSLVNSRCQ EA - Positive Samples: Mouse heart
Target Information
The cystatin superfamily is a well-established family of cysteine protease inhibitors.
Cystatins A and B (type 1) are mainly intracellular; cystatins C, D, E/M, F, G, S, SN, and SA are extracellular (type 2); and kininogens are type 3 cystatins found in the vasculature.
All true cystatins inhibit cysteine peptidases of the papain family (e.g., cathepsins) and some also inhibit legumain family enzymes.
Cystatin SA, S, and SN are primarily found in saliva, while cystatin S and SN are also expressed in tears, urine, and seminal fluid.
Cystatin C is expressed in the brain, thymus, ovary, epididymis, and vas deferens.
Cystatin D protects against oral proteinases, whereas cystatin E/M and F modulate cathepsin inhibition.
Fetuins, part of the cystatin superfamily, regulate osteogenesis, bone resorption, insulin and hepatocyte growth factor receptor activity, and systemic inflammation response.
High and low molecular weight kininogens inhibit thrombin- and plasmin-induced thrombocyte aggregation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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