Thermo Fisher Scientific P2RX6 Polyclonal Antibody
Rabbit polyclonal antibody targeting human P2RX6, validated for WB and IHC. Recognizes a synthetic peptide from aa 350–400 of P2X6. Suitable for research use in skeletal muscle and endothelial cell studies. Lyophilized form, reconstitute in sterile water.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry - Free Floating (IHC (Free)) | 1:300 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from aa region 350–400 of human P2X6 conjugated to blue carrier protein was used as the antigen. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4 °C for short term. For long-term storage, store at −20 °C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- The antigen shares 90% identity with mouse and rat sequences.
- Specificity: P2RX6.
Target Information
P2RX6 encodes receptors that are members of the ligand-gated ion channel family, opening in response to extracellular ATP. Each P2RX6 receptor is composed of a trimer of subunits (P2X1–7) sharing two transmembrane domains. The protein is predominantly expressed in skeletal muscle and regulated by p53. It associates with VE-cadherin at adherens junctions of human umbilical vein endothelial cells. Alternative splicing results in multiple transcript variants of P2RX6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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