Thermo Fisher Scientific Phospho-DNM1L (Ser529) Polyclonal Antibody
Phospho-DNM1L (Ser529) 특이적 폴리클로날 항체로, 인산화된 DRP1 단백질 검출에 적합합니다. Western blot, IHC, ICC/IF에 사용 가능하며, 인간, 마우스, 랫트 반응성을 가집니다. 고순도 정제 및 안정한 액상 형태로 연구용에 적합합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human DNM1L (Accession O00429), corresponding to amino acid residues around phosphorylated Ser529 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816803 |
Product Specific Information
This antibody detects endogenous levels of DRP1 only when phosphorylated at Ser529.
Target Information
Dynamin-related protein 1 (DRP1) is a human protein involved in mitochondrial division in mammalian cells. It regulates mitochondrial fission both at steady state and during apoptosis. DRP1 is essential for proper mitochondrial distribution within cells. In mutant neurons lacking functional DRP1, mitochondria are largely absent from synapses, providing a valuable model to study mitochondrial roles in synaptic function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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