Thermo Fisher Scientific Nanog Monoclonal Antibody (23D2-3C6), DyLight 650
인간 Nanog 단백질을 인식하는 Mouse IgG1 단클론 항체로 DyLight 650 형광 표지. ICC/IF에 적합하며 줄기세포 및 분화 연구에 유용. 단백질 A 정제, PBS 완충액 및 안정화제 포함. 4°C 보관, 동결 금지.
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Thermo Fisher Scientific Nanog Monoclonal Antibody (23D2-3C6), DyLight 650
Applications
- Immunocytochemistry (ICC/IF)
Tested Dilution: 1:10–1:250
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 23D2-3C6 |
| Immunogen | Full-length human recombinant protein expressed in bacteria |
| Conjugate | DyLight™ 650 |
| Excitation / Emission Max | 651 / 673 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.02% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2536680 |
Additional Formats
Product Specific Information
MA1-017-D650 has been successfully used in ICC/IF applications with human samples.
Target Information
NANOG (Nanog homeobox) is a divergent homeodomain protein that regulates pluripotency and differentiation of undifferentiated embryonic stem cells. NANOG mRNA is expressed in pluripotent mouse and human cell lines and absent from differentiated cells. Human NANOG shares 52% overall amino acid identity with mouse NANOG and 85% identity within the homeodomain.
Human NANOG maps to gene locus 12p13.31, while mouse NANOG maps to 6 F2.
Research indicates that NANOG expression is high in undifferentiated N-Tera embryonal carcinoma cells and plays a key role in cell proliferation and self-renewal.
NANOG, together with transcription factors such as Oct-4 (POU5F1), Sox2, Klf4, Lin28, and c-Myc, contributes to the generation of induced pluripotent stem (iPS) cells, offering potential applications in regenerative medicine and treatment of degenerative diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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