Thermo Fisher Scientific PARN Monoclonal Antibody (OTI4C9), TrueMAB
Human PARN 단백질을 인식하는 Mouse monoclonal antibody로 Western blot 및 IHC에 사용 가능. Lyophilized 형태로 제공되며, PBS buffer에 trehalose 포함. 연구용으로만 사용하며 재구성 및 conjugation 실험에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4C9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–266 of human PARN produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments, perform an additional desalting step (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The PARN protein is a 3′-exoribonuclease similar to the RNase D family, preferring poly(A) as a substrate and efficiently degrading mRNA poly(A) tails.
It plays a role in mRNA decay, maternal mRNA silencing during oocyte maturation and embryonic development, and nonsense-mediated decay (NMD) of mRNAs with premature stop codons.
Alternative splicing generates multiple isoforms of this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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