Thermo Fisher Scientific EHHADH Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 444-723 of human EHHADH (NP_001957.2). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:EHHADH,uniProtId:Q08426-1,ncbiNodeId:9606,antigenRange:444-723,antigenLength:723,antigenImageFileName:PA5-109679_EHHADH_Q08426-1_Rabbit.svg,antigenImageFileNamePDP:PA5-109679_EHHADH_Q08426-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.31 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2855090

Product Specific Information

Immunogen sequence: EVIPSQYSSP TTIATVMNLS KKIKKIGVVV GNCFGFVGNR MLNPYYNQAY FLLEEGSKPE EVDQVLEEFG FKMGPFRVSD LAGLDVGWKS RKGQGLTGPT LLPGTPARKR GNRRYCPIPD VLCELGRFGQ KTGKGWYQYD KPLGRIHKPD PWLSKFLSRY RKTHHIEPRT ISQDEILERC LYSLINEAFR ILGEGIAASP EHIDVVYLHG YGWPRHKGGP MFYASTVGLP TVLEKLQKYY RQNPDIPQLE PSDYLKKLAS QGNPPLKEWQ SLAGSPSSKL

Target Information

As an L-hydroxy-specific enzyme, EHHADH (enoyl-CoA-hydratase:3-hydroxyacyl-CoA dehydrogenase), also known as Peroxisomal L-bifunctional enzyme, is a 723 amino acid protein has an essential tripeptide sequence on its carboxyl-terminus that is required for peroxisomal transport. EHHADH- mice only exhibit a blunted peroxisome proliferative response when challenged with a peroxisome proliferator. Since there were no observed changes in lipid metabolism, this evidence suggests that enoyl-CoAs were diverted to the D-hydroxy-specific beta-oxidation system for metabolism.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.