Thermo Fisher Scientific SUMO1 Recombinant Rabbit Monoclonal Antibody (ARC0215)
SUMO1 단백질을 인식하는 recombinant rabbit monoclonal 항체로, Western blot, IHC, ICC/IF, ELISA 등 다양한 응용에 적합. 높은 특이성과 재현성을 제공하며, HEK293 세포에서 발현된 정제 항체. 연구용으로만 사용 가능.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific SUMO1 Recombinant Rabbit Monoclonal Antibody (ARC0215)
Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:2,000–1:10,000 |
| Immunocytochemistry (ICC/IF) | 1:200–1:400 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC0215 |
| Immunogen | Synthetic peptide corresponding to amino acids 1–101 of human SUMO1 (UniProt ID: P63165) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.8 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849174 |
Product Specific Information
Immunogen sequence:
MSDQEAKPST EDLGDKKEGE YIKLKVIGQD SSEIHFKVKM TTHLKKLKES YCQRQGVPMN SLRFLFEGQR IADNHTPKEL GMEEEDVIEV YQEQTGGHST V
Target Information
SUMO1 is a ubiquitin-like protein that can be covalently attached to proteins as a monomer or as lysine-linked polymers. This modification requires activation by the E1 complex (SAE1-SAE2), conjugation via the E2 enzyme UBE2I, and can be facilitated by E3 ligases such as PIAS1–4, RANBP2, or CBX4.
SUMO1 modification plays a key role in cellular processes including nuclear transport, DNA replication and repair, mitosis, and signal transduction. It is involved in targeting RANGAP1 to the nuclear pore complex protein RANBP2. Polymeric SUMO1 chains are susceptible to polyubiquitination, signaling for proteasomal degradation.
SUMO1 may also regulate gene networks involved in palate development, and mutations in this gene can cause non-syndromic orofacial cleft 10.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.