Thermo Fisher Scientific MRVI1 Polyclonal Antibody
Human MRVI1 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western Blot 및 IHC(Paraffin)에 적합. 항원 친화 크로마토그래피로 정제된 고순도 시약. MCF-7 세포를 양성 대조로 권장하며, 장기 보관은 -20°C에서 권장.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
- Publications: [References available]
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:1,000
- Publications: [References available]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein fragment corresponding to a region within amino acids 404–547 of Human MRVI1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2549584 |
Product Specific Information
- Recommended positive control: MCF-7
- Predicted reactivity: Rat (86%), Bovine (88%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene is similar to a putative mouse tumor suppressor gene (Mrvi1) that is frequently disrupted by mouse AIDS-related virus (MRV).
The encoded protein, found in the endoplasmic reticulum membrane, is similar to Jaw1, a lymphoid-restricted protein downregulated during lymphoid differentiation.
Studies in mouse suggest that MRV integration at Mrvi1 induces myeloid leukemia by altering expression of a gene important for myeloid cell growth and/or differentiation.
This gene may function as a myeloid leukemia tumor suppressor gene. Several alternatively spliced transcript variants encoding different isoforms have been found, some initiating translation at a non-AUG (CUG) start site.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: PA5-32111_MRVI1_Q9Y6F6-9_Rabbit.svg, PA5-32111_MRVI1_Q9Y6F6-9_Rabbit_PDP.jpeg)
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