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Thermo Fisher Scientific Reticulon 1 Polyclonal Antibody
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Thermo Fisher Scientific Reticulon 1 Polyclonal Antibody

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Thermo Fisher Scientific의 Reticulon 1 폴리클로날 항체는 마우스 및 랫트 반응성을 가지며, WB 및 IHC에 사용 가능. 합성 펩타이드 항원을 기반으로 제작되어 신경 및 신경내분비 조직 특이적 단백질 연구에 적합. 연구용으로만 사용 가능.

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마지막 업데이트 2025. 08. 04. 오전 05:03
Thermo Fisher Scientific OSR00352W-100UL Reticulon 1 Polyclonal Antibody 100 ul pk판매 단위 pk ·
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563,100원VAT 포함 619,410원

Thermo Fisher Scientific · Thermo Fisher Scientific Reticulon 1 Polyclonal Antibody

Applications

Application Tested Dilution Publications
Western Blot (WB) 1:300–1:2,000 -
Immunohistochemistry (IHC) 1:300–1:2,000 -
Miscellaneous PubMed (Misc) - View 2 publications

Product Specifications

Specification Description
Species Reactivity Mouse, Rat
Published Species Not Applicable
Host / Isotype Rabbit / Ig
Class Polyclonal
Type Antibody
Immunogen A synthetic peptide corresponding to amino acid region 170–220 of mouse Reticulon 1 conjugated to blue carrier protein
Conjugate Unconjugated
Form Lyophilized
Concentration Not Determined
Storage Buffer Whole serum
Contains No preservative
Storage Conditions Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping Conditions Ambient (domestic); Wet ice (international)

Product Specific Information

  • Reconstitute in 100 µL of sterile water.
  • Centrifuge to remove any insoluble material.
  • The peptide is homologous in rat.
  • Specificity of this antibody: RTN1.

Target Information

Reticulon-1 (formerly designated NSP for Neuroendocrine-Specific-Protein) is specifically expressed in neural and neuroendocrine tissues.
The NSP gene is mapped to human chromosome 14q21–q22 and encodes three overlapping proteins: reticulon-1A (NSP-A), reticulon-1B (NSP-B), and reticulon-1C (NSP-C).
These proteins are anchored to endoplasmic reticulum membranes via their common C-terminal regions.

  • Reticulon-1A: ~135 kDa, occurs in multiple isoforms depending on phosphorylation; a reliable marker for neuroendocrine differentiation in lung cancer diagnosis (SCLC and carcinoid tumors).
  • Reticulon-1B: ~45 kDa phosphoprotein, restricted to lung cancer cell line NCI-H82, not found in human tissues.
  • Reticulon-1C: ~23 kDa non-phosphorylated protein, found with Reticulon-1A in SCLC cell lines but not in non-SCLC cultures.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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