Thermo Fisher Scientific GABRA3 Polyclonal Antibody
Rabbit polyclonal antibody targeting GABRA3 for WB and ELISA applications. Reacts with human, mouse, and rat. Affinity purified, supplied in PBS with 50% glycerol. For research use only.
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- PA588192
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 29–276 of human GABRA3 (NP_000799.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.48 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | –20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804732 |
Product Specific Information
Immunogen sequence:
QGESRRQEPG DFVKQDIGGL SPKHAPDIPD DSTDNITIFT RILDRLLDGY DNRLRPGLGD AVTEVKTDIY VTSFGPVSDT DMEYTIDVFF RQTWHDERLK FDGPMKILPL NNLLASKIWT PDTFFHNGKK SVAHNMTTPN KLLRLVDNGT LLYTMRLTIH AECPMHLEDF PMDVHACPLK FGSYAYTTAE VVYSWTLGKN KSVEVAQDGS RLNQYDLLGH VVGTEIIRSS TGEYVVMTTH FHLKRKIG
Positive Samples: SH-SY5Y, Mouse kidney, Rat liver
Cellular Location: Cell junction, Cell membrane, Multi-pass membrane protein, postsynaptic cell membrane, synapse
Target Information
GABA is the major inhibitory neurotransmitter in the mammalian brain, acting at GABA-A receptors which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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