Thermo Fisher Scientific GABRA3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 29-276 of human GABRA3 (NP_0007991) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GABRA3,uniProtId:P34903-1,ncbiNodeId:9606,antigenRange:29-276,antigenLength:492,antigenImageFileName:PA5-88192_GABRA3_P34903-1_Rabbit.svg,antigenImageFileNamePDP:PA5-88192_GABRA3_P34903-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.48 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2804732

Product Specific Information

Immunogen sequence: QGESRRQEPG DFVKQDIGGL SPKHAPDIPD DSTDNITIFT RILDRLLDGY DNRLRPGLGD AVTEVKTDIY VTSFGPVSDT DMEYTIDVFF RQTWHDERLK FDGPMKILPL NNLLASKIWT PDTFFHNGKK SVAHNMTTPN KLLRLVDNGT LLYTMRLTIH AECPMHLEDF PMDVHACPLK FGSYAYTTAE VVYSWTLGKN KSVEVAQDGS RLNQYDLLGH VVGTEIIRSS TGEYVVMTTH FHLKRKIG; Positive Samples: SH-SY5Y, Mouse kidney, Rat liver; Cellular Location: Cell junction, Cell membrane, Multi-pass membrane protein, postsynaptic cell membrane, synapse

Target Information

GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.