Thermo Fisher Scientific Phospho-MEK1/MEK2 (Ser217, Ser221) Monoclonal Antibody (C.158.9)
Phospho-MEK1/MEK2 (Ser217/221) 특이적 단일클론 항체로, Western blot 및 Immunoprecipitation에 적합. 인간, 마우스, 원숭이, 랫트 반응성. Rabbit IgG 유래, 비결합형 액상 시약. 세포 성장 및 분화 조절 연구에 활용.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 1 publication |
| Immunoprecipitation (IP) | 1:50 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C.158.9 |
| Immunogen | Synthetic phosphopeptide corresponding to residues around pSer217/221 of human MEK1/2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 26 µg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES (pH 7.5), 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | <0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_10977854 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
MEK1 (MAP Kinase Kinase, also known as MKK) is an integral component of the MAP kinase cascade that regulates cell growth and differentiation (Ahn, 1993; Chong et al., 2003). In brain, this pathway also plays a key role in synaptic regulation (Adams and Sweatt, 2002). Activated MEK1 acts as a dual specificity kinase phosphorylating both a threonine and a tyrosine residue on MAP kinase (Kyriakis et al., 1991; Seger et al., 1991; Crews et al., 1992).
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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