
Thermo Fisher Scientific Parkin Polyclonal Antibody
Parkin 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB 및 IHC에 적합. 인간, 마우스, 랫트 반응성. 합성 펩타이드 면역원 사용. PBS 버퍼에 보존되며 장기 보관 시 -20°C 권장. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 10–50 µg/mL
- Publications: 2 publications
Immunohistochemistry (IHC)
- Tested Dilution: 10–50 µg/mL
- Publications: 2 publications
Miscellaneous PubMed (Misc)
- Publications: 2 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the C-terminal of Parkin (PARK2, Parkinson disease protein 2) conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
- The antigen is homologous in rat and shares 95% identity with mouse sequence.
- Specificity: Parkin.
Target Information
The precise function of the Parkin gene is unknown; however, the encoded protein is part of a multiprotein E3 ubiquitin ligase complex that mediates proteasomal degradation of substrate proteins.
Mutations in this gene are associated with Parkinson disease and autosomal recessive juvenile Parkinson disease.
Alternative splicing produces multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but currently lack transcript support.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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