Thermo Fisher Scientific ALDH1B1 Polyclonal Antibody
ALDH1B1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF에 적합합니다. 인간 및 생쥐 반응성을 가지며, 고순도 친화 크로마토그래피로 정제된 액상 항체입니다. 연구용으로 에탄올 해독 관련 ALDH1B1 단백질 분석에 활용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human ALDH1B1 (Accession P30837), corresponding to amino acid residues A343–E393 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850848 |
Product Specific Information
This antibody detects endogenous levels of total ALDH1B1.
Target Information
Aldehyde dehydrogenases (ALDHs) mediate NADP⁺-dependent oxidation of aldehydes into acids during detoxification of alcohol-derived acetaldehyde, lipid peroxidation, and metabolism of corticosteroids, biogenic amines, and neurotransmitters.
Alcohol consumption habits and cardiovascular disease risk factors may be associated with ALDH gene variants.
ALDH1B1 (Aldehyde dehydrogenase family 1 member B1), also known as ALDH5 or ALDHX (Aldehyde dehydrogenase X, mitochondrial), is a 517-amino-acid mitochondrial protein expressed in the liver, testis, and to a lesser extent in the brain.
It belongs to the aldehyde dehydrogenase family and may play a major role in ethanol detoxification.
For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.
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