Thermo Fisher Scientific KIF3A Polyclonal Antibody
KIF3A 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 적합하며 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제, 동결건조 형태로 제공. 연구용으로만 사용 가능.
- 판매단위
- pk
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Thermo Fisher Scientific KIF3A Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 0.1–0.5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E.coli-derived human KIF3A recombinant protein (Position: D485–Q699) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5 mg BSA |
| Contains | 0.05 mg sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2746670 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
The kinesins constitute a large family of microtubule-dependent motor proteins responsible for distributing organelles, vesicles, and macromolecular complexes throughout the cell.
Members of the heterotrimeric kinesin II family generally contain two different motor subunits from the KIF3 family (KIF3A, KIF3B, KIF3C).
KIF3 isoforms mediate anterograde transport of membrane-bound organelles in neurons and melanosomes, transport between the endoplasmic reticulum and Golgi, and movement of protein complexes within cilia and flagella required for morphogenesis.
KIF3A may influence neurogenesis and left-right axis determination during embryonic development.
Loss of KIF3A function in mouse photoreceptors causes apoptotic cell death, indicating kinesin II-mediated transport is required for proper cell fate.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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