
Thermo Fisher Scientific SDHAF1 Monoclonal Antibody (OTI8F10), TrueMAB
인간 SDHAF1 단백질을 인식하는 단클론 항체로 Western blot에 적합. 무보존제, 동결건조 형태로 제공되며, 재구성 후 1 mg/mL 농도로 사용 가능. SDH 복합체 조립 연구 및 미토콘드리아 관련 연구에 유용.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8F10 |
| Immunogen | Full length human recombinant protein of human SDHAF1 produced in 293T |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional round of desalting.
Recommended product: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
SDHAF1 (Succinate dehydrogenase complex assembly factor 1) is a mitochondrial protein essential for assembly of the succinate dehydrogenase (SDH) complex (complex II) of the respiratory chain.
It does not physically associate with the complex in vivo.
Mutations in SDHAF1 are linked to SDH-defective infantile leukoencephalopathy (mitochondrial complex II deficiency).
Unlike SDHAF2, SDHAF1 is not considered a tumor suppressor.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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