Thermo Fisher Scientific SDHAF1 Monoclonal Antibody (OTI5C1), TrueMAB
인간 SDHAF1 단백질을 인식하는 단클론 항체로 Western blot에 적합. 마우스 IgG1 형식이며 비결합형, 동결건조 상태로 제공. 연구용으로만 사용되며 SDH 복합체 조립 연구에 유용.
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Applications
- Western Blot (WB): Tested at 1:500 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5C1 |
| Immunogen | Full length human recombinant protein of human SDHAF1 produced in 293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
SDHAF1 (Succinate dehydrogenase complex assembly factor 1) is a mitochondrial protein essential for the assembly of the succinate dehydrogenase (SDH) complex (complex II) in the respiratory chain. It does not physically associate with the complex in vivo.
Mutations in SDHAF1 are linked to SDH-defective infantile leukoencephalopathy (mitochondrial complex II deficiency).
Unlike SDHAF2, SDHAF1 is not considered a tumor suppressor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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