Thermo Fisher Scientific MRPL28 Recombinant Rabbit Monoclonal Antibody (JE55-90)
MRPL28 단백질을 인식하는 토끼 단클론 항체로, WB, IHC, ICC, Flow Cytometry에 적합합니다. 인간, 마우스, 랫드, 제브라피시에 반응하며, 미토콘드리아 단백질 연구에 유용합니다. Protein A 정제, 1 mg/mL 농도, 비결합형 액상 포맷입니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:100 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Zebrafish, Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JE55-90 |
| Immunogen | Synthetic peptide within N-terminal Human MRPL28 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2911651 |
Product Specific Information
- Positive Control: Mouse liver tissue lysate, SW480 cell lysate, rat stomach tissue lysate, human skin tissue lysate, A549 cell lysate, K562 cell lysate, Hela cell lysate, zebrafish tissue lysates, 293T, MCF-7, SW480, human tonsil tissue, human liver tissue, human liver carcinoma tissue.
- Subcellular Location: Mitochondrion.
Target Information
MRP-L28 (39S ribosomal protein L28, melanoma-associated antigen recognized by T lymphocytes) is a mitochondrial protein belonging to the ribosomal protein L28P family.
MRP-L28 may serve as a therapeutic reagent for HLA-A24 (A24) patients, as it is recognized by tumor-infiltrating lymphocyte (TIL) 1290, which targets the A24 serotype.
HLA-A24 (A24) is an HLA-A serotype identifying common HLA-A24 gene products. It is related to A9 and A23 antigen types and is prevalent in Austronesian populations, including Papua New Guineans, indigenous Taiwanese, Yupik, and Greenland Eskimos.
MRP-L28 is expressed in various normal tissues such as spleen, testis, thymus, liver, kidney, brain, adrenal, lung, and retina.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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