
Thermo Fisher Scientific Desmocollin 3 Recombinant Rabbit Monoclonal Antibody (JE55-86)
Desmocollin 3 단백질을 인식하는 토끼 단클론 항체로, Western blot 및 IHC(P)에서 검증됨. 인간, 마우스, 랫트 반응성. HEK293 세포 발현, Protein A 정제, 1 mg/mL 농도. 세포막 및 데스모좀 위치 단백질 연구용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JE55-86 |
| Immunogen | Synthetic peptide within C-terminal Human Desmocollin 3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2911648 |
Product Specific Information
- Positive Control: Rat skin tissue lysate, A431 cell lysate, 293T, human skin tissue, mouse esophagus tissue, A431
- Subcellular Location: Cell membrane, desmosome
Target Information
Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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