Thermo Fisher Scientific TSHZ2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human TSHZ2. Recombinant protein control fragment (Product #RP-89417). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TSHZ2,uniProtId:Q9NRE2-1,ncbiNodeId:9606,antigenRange:36-175,antigenLength:1034,antigenImageFileName:PA5-58255_TSHZ2_Q9NRE2-1_Rabbit.svg,antigenImageFileNamePDP:PA5-58255_TSHZ2_Q9NRE2-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.20 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2648996

Product Specific Information

Immunogen sequence: SGSVAQLQGG NDTGTDEELE TGPEQKGCFS YQNSPGSHLS NQDAENESLL SDASDQVSDI KSVCGRDASD KKAHTHVRLP NEAHNCMDKM TAVYANILSD SYWSGLGLGF KLSNSERRNC DTRNGSNKSD FDWHQDALSK

Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 90%.

Target Information

The Teashirt zinc finger homeobox (TSHZ) family comprise a family of evolutionarily conserved transcription factors that, in Drosophila, are active in specific body parts for patterning, but whose function in vertebrates is less clear. In mice, the known three TSHZ proteins are expressed in distinct patterns in the developing and adult brain, suggesting that they play a role in the establishment of regional identity and specification of cell types within the brain. Recent experiments have shown that the expression of TSHZ2 is frequently downregulated in most breast and prostate cancers and its promoter was unmethylated in virtually all cases, suggesting this family of proteins may also be involved in carcinogenesis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.