Thermo Fisher Scientific TSHZ2 Polyclonal Antibody
Human TSHZ2 단백질을 인식하는 Rabbit Polyclonal Antibody로 IHC(P) 및 ICC/IF에 적합. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol buffer에 보관. 암 연구 및 신경 발달 관련 연구용으로 사용 가능.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:500
Immunocytochemistry (ICC/IF)
- Tested Concentration: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human TSHZ2 (control fragment: Product #RP-89417) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C (avoid freeze/thaw cycles). |
| Shipping Conditions | Wet ice |
| RRID | AB_2648996 |
Product Specific Information
Immunogen sequence:
SGSVAQLQGG NDTGTDEELE TGPEQKGCFS YQNSPGSHLS NQDAENESLL SDASDQVSDI KSVCGRDASD KKAHTHVRLP NEAHNCMDKM TAVYANILSD SYWSGLGLGF KLSNSERRNC DTRNGSNKSD FDWHQDALSK- Highest antigen sequence identity to orthologs:
- Mouse: 89%
- Rat: 90%
Target Information
The Teashirt zinc finger homeobox (TSHZ) family comprises a group of evolutionarily conserved transcription factors. In Drosophila, they are involved in body patterning, while their function in vertebrates remains less clear. In mice, three known TSHZ proteins are expressed in distinct patterns in the developing and adult brain, suggesting roles in regional identity and cell type specification.
Recent studies indicate that TSHZ2 expression is frequently downregulated in breast and prostate cancers, with an unmethylated promoter, implying a potential role in carcinogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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