Thermo Fisher Scientific NCDN Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human NCDN. Recombinant protein control fragment (Product #RP-93982). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:NCDN,uniProtId:Q9UBB6-1,ncbiNodeId:9606,antigenRange:624-721,antigenLength:729,antigenImageFileName:PA5-54863_NCDN_Q9UBB6-1_Rabbit.svg,antigenImageFileNamePDP:PA5-54863_NCDN_Q9UBB6-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2644512

Product Specific Information

Immunogen sequence: PEYEGIWADL QELWFLGMQA FTGCVPLLPW LAPAALRSRW PQELLQLLGS VSPNSVKPEM VAAYQGVLVE LARANRLCRE AMRLQAGEET ASHYRMAA

Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.

Target Information

Probably involved in signal transduction, in the nervous system, via increasing cell surface localization of GRM5 and positively regulating its signaling. Required for the spatial learning process. Acts as a negative regulator of Ca(2+)-calmodulin-dependent protein kinase 2 (CaMK2) phosphorylation. May play a role in modulating melanin-concentrating hormone-mediated functions via its interaction with MCHR1 that interferes with G protein-coupled signal transduction. May be involved in bone metabolism. May also be involved in neurite outgrowth.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.